Question

A 70-year-old on apixaban 5 mg twice daily for AF is scheduled for elective laparoscopic cholecystectomy (moderate bleeding risk). Renal function is normal. How should apixaban be managed?

Accepted Answer

Hold for 48 hours pre-op without bridging

Answer

Continue apixaban through surgery

Answer

Hold for 24 hours pre-op without bridging

Answer

Hold for 48 hours and bridge with LMWH

Answer

Switch to warfarin 1 week before surgery

Practice question

A 70-year-old on apixaban 5 mg twice daily for AF is scheduled for elective laparoscopic cholecystectomy (moderate bleeding risk). Renal function is normal. How should apixaban be managed?