Question

A 62-year-old with COPD has an acute exacerbation with sputum purulence and dyspnea but no pneumonia. In addition to prednisone, which antibiotic approach is reasonable?

Accepted Answer

Azithromycin or doxycycline or amoxicillin-clavulanate for 5-7 days

Answer

No antibiotics for any exacerbation

Answer

Vancomycin and piperacillin-tazobactam for 14 days

Answer

Moxifloxacin for 14 days mandatory

Answer

Trimethoprim-sulfamethoxazole for 3 days

Practice question

A 62-year-old with COPD has an acute exacerbation with sputum purulence and dyspnea but no pneumonia. In addition to prednisone, which antibiotic approach is reasonable?