Question

A 64-year-old woman with HFrEF and persistent volume overload on loop diuretic alone. What diuretic strategy is evidence-based?

Accepted Answer

Add a thiazide-like diuretic (e.g., metolazone) short-term for diuretic synergy

Answer

Stop loop diuretic

Answer

Start MRA solely for diuresis

Answer

Fluid restriction only

Answer

Add acetazolamide without indication

Practice question

A 64-year-old woman with HFrEF and persistent volume overload on loop diuretic alone. What diuretic strategy is evidence-based?