Question

A 58-year-old with gout and recurrent flares (≥2/year), serum urate 9.0 mg/dL, normal renal function. Best urate-lowering strategy?

Accepted Answer

Allopurinol starting 100 mg daily with titration to target <6 mg/dL

Answer

Febuxostat 80 mg daily as first-line regardless of comorbidities

Answer

Probenecid first-line in all

Answer

No ULT; treat flares only

Answer

Allopurinol 300 mg daily starting dose without titration

Practice question

A 58-year-old with gout and recurrent flares (≥2/year), serum urate 9.0 mg/dL, normal renal function. Best urate-lowering strategy?