Question

A 32-year-old female with watery diarrhoea after clindamycin has positive C. difficile NAAT and toxin. First episode, non-severe. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO BID 10 days preferred over vancomycin

Answer

Metronidazole 500 mg PO TID 10 days

Answer

Vancomycin 125 mg PO QID 10 days preferred over fidaxomicin

Answer

Rifaximin 400 mg PO TID 10 days

Answer

Probiotics alone

Practice question

A 32-year-old female with watery diarrhoea after clindamycin has positive C. difficile NAAT and toxin. First episode, non-severe. Best initial therapy?