Question

A 33-year-old with gout and recurrent flares (3/year), urate 9.2 mg/dL, eGFR 65. Optimal urate‑lowering strategy?

Accepted Answer

Start allopurinol ≤100 mg daily and titrate to urate <6 mg/dL with flare prophylaxis

Answer

Start allopurinol 300 mg daily immediately

Answer

Colchicine daily without urate lowering

Answer

Probenecid first‑line

Answer

Febuxostat first‑line regardless of history

Practice question

A 33-year-old with gout and recurrent flares (3/year), urate 9.2 mg/dL, eGFR 65. Optimal urate‑lowering strategy?