Question

A 62-year-old hospitalized patient develops non-fulminant first-episode Clostridioides difficile infection (diarrhea, positive toxin). Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg orally three times daily for 14 days

Answer

Oral vancomycin 250 mg four times daily for 14 days

Answer

Bezlotoxumab alone single infusion

Answer

Probiotics alone

Practice question

A 62-year-old hospitalized patient develops non-fulminant first-episode Clostridioides difficile infection (diarrhea, positive toxin). Best initial therapy?