Question

An ED patient with anaphylaxis (airway swelling, urticaria, hypotension) weighs 80 kg. What is the first-line treatment and dose?

Accepted Answer

Epinephrine 0.3-0.5 mg IM in the anterolateral thigh, repeat every 5-15 min as needed

Answer

Diphenhydramine 50 mg IV, then observe

Answer

Methylprednisolone 125 mg IV immediately as monotherapy

Answer

Normal saline only, avoid epinephrine due to tachycardia

Answer

Epinephrine IV bolus 1 mg immediately

Practice question

An ED patient with anaphylaxis (airway swelling, urticaria, hypotension) weighs 80 kg. What is the first-line treatment and dose?