Question

A 66-year-old man with C. difficile infection (first recurrence; nonsevere) asks about adjunctive therapy to reduce future recurrences. He is ≥65 with multiple comorbidities. Which option is guideline-supported?

Accepted Answer

Add bezlotoxumab during standard-of-care antibiotics

Answer

Add rifaximin for 3 months

Answer

Oral vancomycin prophylaxis for 6 months

Answer

Probiotics only

Answer

No adjuncts reduce recurrence risk

Practice question

A 66-year-old man with C. difficile infection (first recurrence; nonsevere) asks about adjunctive therapy to reduce future recurrences. He is ≥65 with multiple comorbidities. Which option is guideline-supported?