Question

A 60-year-old with gout and CKD stage 3 is starting urate-lowering therapy. What initiation strategy is recommended?

Accepted Answer

Start allopurinol ≤100 mg daily (≤50 mg if CKD) and titrate to serum urate <6 mg/dL

Answer

Start allopurinol 300 mg daily and titrate down

Answer

Start febuxostat 80 mg daily first-line in all CKD

Answer

Begin probenecid monotherapy

Answer

Avoid anti-inflammatory prophylaxis during ULT initiation

Practice question

A 60-year-old with gout and CKD stage 3 is starting urate-lowering therapy. What initiation strategy is recommended?