Question

A 28-year-old with watery diarrhea and positive NAAT for C. difficile (nonfulminant, first episode) seeks treatment. Best initial therapy?

Accepted Answer

Oral fidaxomicin 200 mg twice daily for 10 days (preferred)

Answer

Oral metronidazole for 10 days

Answer

Oral vancomycin 125 mg QID for 10 days (preferred over fidaxomicin)

Answer

Probiotics only

Answer

Rifaximin monotherapy

Practice question

A 28-year-old with watery diarrhea and positive NAAT for C. difficile (nonfulminant, first episode) seeks treatment. Best initial therapy?