Question

A 70-year-old with HFrEF and persistent symptoms despite ACEi, beta-blocker, MRA, SGLT2 asks about hydralazine/isosorbide dinitrate. Indication?

Accepted Answer

Add for persistent symptoms in African American patients on optimal therapy

Answer

All HFrEF patients should receive it first-line

Answer

Contraindicated with ACEi

Answer

Replace ACEi with hydralazine

Answer

Use only post-MI

Practice question

A 70-year-old with HFrEF and persistent symptoms despite ACEi, beta-blocker, MRA, SGLT2 asks about hydralazine/isosorbide dinitrate. Indication?