Question

A 57-year-old woman presents with community-onset watery diarrhea after receiving ceftriaxone for a urinary tract infection. Stool testing is positive for C. difficile toxin. She experienced a Clostridioides difficile infection (CDI) 3 months ago. What is the best therapy now?

Accepted Answer

Fidaxomicin (standard or extended-pulsed)

Answer

Repeat metronidazole

Answer

Vancomycin 125 mg QID for 10 days

Answer

Bezlotoxumab monotherapy

Answer

Stop antibiotics only

Practice question

A 57-year-old woman presents with community-onset watery diarrhea after receiving ceftriaxone for a urinary tract infection. Stool testing is positive for C. difficile toxin. She experienced a Clostridioides difficile infection (CDI) 3 months ago. What is the best therapy now?