Question

A 59-year-old with initial episode of nonsevere Clostridioides difficile infection asks about therapy. Optimal first-line treatment?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg three times daily for 10 days

Answer

Vancomycin 125 mg orally four times daily for 10 days (preferred over fidaxomicin)

Answer

Bezlotoxumab monotherapy

Answer

Probiotics only

Practice question

A 59-year-old with initial episode of nonsevere Clostridioides difficile infection asks about therapy. Optimal first-line treatment?