Question

A 65-year-old with AF and prior stroke (CHA₂DS₂‑VASc 4) is scheduled for elective total hip arthroplasty (high bleeding risk). On apixaban, normal renal function. Perioperative timing?

Accepted Answer

Stop apixaban ~2 days before; resume 48-72 hours after if hemostasis secure

Answer

Stop apixaban 12 hours before and resume next morning

Answer

Bridge apixaban with heparin

Answer

Continue apixaban without interruption

Answer

Switch to warfarin 1 week before

Practice question

A 65-year-old with AF and prior stroke (CHA₂DS₂‑VASc 4) is scheduled for elective total hip arthroplasty (high bleeding risk). On apixaban, normal renal function. Perioperative timing?