Question

A 35-year-old with watery diarrhea after clindamycin; WBC 13,000/µL, SCr 1.0 (baseline 0.9). First episode C. difficile infection. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Vancomycin 125 mg orally four times daily for 10 days

Answer

Metronidazole 500 mg orally three times daily for 10 days

Answer

Oral vancomycin taper/pulse

Answer

Bezlotoxumab infusion alone

Practice question

A 35-year-old with watery diarrhea after clindamycin; WBC 13,000/µL, SCr 1.0 (baseline 0.9). First episode C. difficile infection. Best initial therapy?