Question

A 34-year-old with persistent dyspepsia completed 14-day optimized bismuth quadruple therapy for H. pylori. What is the recommended test-of-cure timing and method?

Accepted Answer

Urea breath test ≥4 weeks after therapy, off PPI for 2 weeks

Answer

Serum IgG H. pylori antibody now

Answer

Repeat endoscopy with rapid urease test in 1 week

Answer

Stool antigen within 48 hours of therapy completion

Answer

No test-of-cure is needed after first-line therapy

Practice question

A 34-year-old with persistent dyspepsia completed 14-day optimized bismuth quadruple therapy for H. pylori. What is the recommended test-of-cure timing and method?