Question

A 58-year-old with chronic hepatitis B is HBsAg-positive, HBV DNA high, normal ALT. Which patients require antiviral therapy?

Accepted Answer

Treat based on DNA level, ALT elevation, and fibrosis stage/risk

Answer

All HBsAg-positive patients

Answer

Only if DNA detectable

Answer

Treat only if ALT >5x ULN

Answer

Treat only if symptomatic jaundice

Practice question

A 58-year-old with chronic hepatitis B is HBsAg-positive, HBV DNA high, normal ALT. Which patients require antiviral therapy?