Question

A 61-year-old man on apixaban for AF presents with GI bleeding requiring endoscopic therapy. Which reversal strategy is appropriate prior to urgent procedure?

Accepted Answer

Use andexanet alfa if available for life-threatening bleeding

Answer

Give protamine sulfate

Answer

Give phytonadione (vitamin K)

Answer

No reversal available for DOACs

Answer

Switch to dabigatran

Practice question

A 61-year-old man on apixaban for AF presents with GI bleeding requiring endoscopic therapy. Which reversal strategy is appropriate prior to urgent procedure?