Question

A 32-year-old hiker has an expanding 12-cm annular rash with central clearing and low-grade fever 3 days after a tick bite in New England. No neurologic or cardiac symptoms. Best treatment?

Accepted Answer

Doxycycline 100 mg orally twice daily for 10 days

Answer

Amoxicillin 500 mg orally three times daily for 3 days

Answer

Ceftriaxone 2 g IV daily for 28 days

Answer

No antibiotics; observe

Answer

Topical corticosteroids

Practice question

A 32-year-old hiker has an expanding 12-cm annular rash with central clearing and low-grade fever 3 days after a tick bite in New England. No neurologic or cardiac symptoms. Best treatment?