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ModerateInfectious DiseasesHepatitis B vaccination in immunosuppressed adultus-abfmus-abimus-usmle-step-2us-usmle-step-3

A 50 year old woman with rheumatoid arthritis on methotrexate and low dose prednisone presents for routine follow up. She has no history of hepatitis B vaccination. Laboratory testing shows she is seronegative for hepatitis B surface antigen, surface antibody, and core antibody. According to adult immunisation recommendations, which vaccination strategy is most appropriate?

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