Question

A 25-year-old woman presents with fever, diffuse macular rash starting on the trunk and spreading, and hypotension after tampon use. Labs show elevated AST, ALT, and creatinine. Blood cultures later grow Staphylococcus aureus. What is the most appropriate initial management?

Accepted Answer

IV fluids, vasopressors as needed, and IV antibiotics targeting toxin-producing S. aureus

Answer

Observation and oral antibiotics

Answer

High-dose IV corticosteroids only

Answer

Immediate surgical debridement of soft tissue

Answer

Exchange transfusion

Practice question

A 25-year-old woman presents with fever, diffuse macular rash starting on the trunk and spreading, and hypotension after tampon use. Labs show elevated AST, ALT, and creatinine. Blood cultures later grow Staphylococcus aureus. What is the most appropriate initial management?