Question

A 48-year-old woman presents with fatigue, arthralgia, and a malar rash. Lab tests reveal positive ANA and anti-double-stranded DNA antibodies with low complement levels. Urinalysis shows 2 plus protein and red blood cell casts. What is the most appropriate next step in evaluation?

Accepted Answer

Renal biopsy

Answer

Skin biopsy of the rash

Answer

Liver biopsy

Answer

Bone marrow biopsy

Answer

No further evaluation is needed

Practice question

A 48-year-old woman presents with fatigue, arthralgia, and a malar rash. Lab tests reveal positive ANA and anti-double-stranded DNA antibodies with low complement levels. Urinalysis shows 2 plus protein and red blood cell casts. What is the most appropriate next step in evaluation?