Question

A 30-year-old man with gout has two flares in the past year. Serum urate 9.2 mg/dL, normal renal function. Best long-term urate-lowering strategy?

Accepted Answer

Start allopurinol <=100 mg daily with titration to target <6 mg/dL and prophylaxis

Answer

Start allopurinol 300 mg daily immediately

Answer

Use colchicine PRN only for flares

Answer

Start probenecid as first-line in all patients

Answer

Avoid urate-lowering therapy because flares are infrequent

Practice question

A 30-year-old man with gout has two flares in the past year. Serum urate 9.2 mg/dL, normal renal function. Best long-term urate-lowering strategy?