Question

A 32-year-old woman with new-onset symmetrical polyarthritis is diagnosed with rheumatoid arthritis. According to ACR guidance, what is the initial pharmacologic therapy for moderate-to-high disease activity?

Accepted Answer

Methotrexate monotherapy with treat-to-target strategy

Answer

Hydroxychloroquine monotherapy

Answer

Immediate TNF inhibitor monotherapy without csDMARDs

Answer

NSAIDs alone for 6 months

Answer

Long-term oral glucocorticoids as primary therapy

Practice question

A 32-year-old woman with new-onset symmetrical polyarthritis is diagnosed with rheumatoid arthritis. According to ACR guidance, what is the initial pharmacologic therapy for moderate-to-high disease activity?