Question

A 25-year-old man with cough and fever is diagnosed with outpatient community-acquired pneumonia and has no comorbidities or risk factors. Local macrolide resistance is >25%. Best empiric regimen?

Accepted Answer

High-dose amoxicillin (1 g) three times daily for 5 days

Answer

Azithromycin monotherapy for 5 days

Answer

Levofloxacin 750 mg daily for 5 days

Answer

Amoxicillin-clavulanate 875/125 mg twice daily plus doxycycline

Answer

Clarithromycin monotherapy

Practice question

A 25-year-old man with cough and fever is diagnosed with outpatient community-acquired pneumonia and has no comorbidities or risk factors. Local macrolide resistance is >25%. Best empiric regimen?