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EasyNeurologyAcute Ischemic Strokeus-abemus-usmle-step-2us-usmle-step-3us-abim

A 71-year-old presents 8 hours after sudden right hemiplegia and aphasia. CT head shows no hemorrhage. CT perfusion demonstrates a large penumbra-core mismatch with an M1 proximal occlusion. NIHSS is 16. What is the most appropriate therapy now?

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