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ModerateCardiologyHeart Failure with Reduced Ejection Fractionus-abfmus-abimus-usmle-step-2us-usmle-step-3

A 64-year-old man with ischemic cardiomyopathy (EF 30%), NYHA class II symptoms, diabetes, and chronic kidney disease with eGFR 45 mL/min/1.73 m2 is on lisinopril, carvedilol, and spironolactone. He is euvolemic on exam. Which additional medication has been shown to reduce heart failure hospitalizations and cardiovascular mortality in this setting?

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