Question

A 50-year-old man with BMI 36 kg/m² and hypertension seeks weight loss therapy after lifestyle failure. Which option is guideline-supported?

Accepted Answer

Initiate semaglutide 2.4 mg weekly as adjunct to lifestyle

Answer

Phentermine indefinitely as monotherapy

Answer

Orlistat as first-line due to better efficacy than GLP-1 RA

Answer

Metformin as first-line anti-obesity agent

Answer

No pharmacotherapy until BMI ≥40 kg/m²

Practice question

A 50-year-old man with BMI 36 kg/m² and hypertension seeks weight loss therapy after lifestyle failure. Which option is guideline-supported?