A patient without known cardiovascular disease has untreated LDL cholesterol 5.4 mmol/L and a first-degree relative who had myocardial infarction at 3...

Question

A patient without known cardiovascular disease has untreated LDL cholesterol 5.4 mmol/L and a first-degree relative who had myocardial infarction at 38. What additional action is required alongside starting intensive statin therapy?

Accepted Answer

Familial-hypercholesterolaemia assessment and cascade evaluation

Answer

QRISK-based assessment and coronary calcium scoring

Answer

Secondary-cause assessment followed by dietary treatment

Answer

Genetic confirmation followed by delayed statin treatment

Answer

Ezetimibe monotherapy followed by lipid-clinic review

severe hypercholesterolemia — MRCP Part 1 MCQ

A patient without known cardiovascular disease has untreated LDL cholesterol 5.4 mmol/L and a first-degree relative who had myocardial infarction at 38. What additional action is required alongside starting intensive statin therapy?