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Moderateand naltrexone/bupropion ER are also options. Orlistat (A) is generally not recommended. Chronic phentermine alone (C) lacks long-term approval. Lorcaserin (D) withdrawn. Topiramate alone (E) is not approved as monotherapy for obesity."Obesity"moderate"

A 54-year-old man with obesity (BMI 37) and NAFLD seeks weight loss medication. Which pharmacotherapy is guideline-preferred for long-term management?

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