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Hard"B"In AF with CHA2DS2-VASc >=2 and contraindication to long-term OAC, percutaneous LAAO is reasonable (Class 2a). Aspirin (A) or dual antiplatelet therapy (D) are inferior. Low-intensity warfarin (C) is not guideline-endorsed. No therapy (E) ignores high stroke risk."acc/aha/accp/hrs guideline (2023): atrial fibrillation"

A 73-year-old woman with nonvalvular AF, CHA2DS2-VASc 5, HAS-BLED 4. What stroke-prevention approach is reasonable?

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