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Moderate"ACR 2020 recommends treat‑to‑target ULT (allopurinol first‑line) titrated to SU <6 mg/dL in patients with frequent flares. Colchicine alone does not lower urate; probenecid is alternative; pegloticase is for refractory disease."Rheumatology"moderate"

A 52-year-old with recurrent gout flares (>=3/year) and normal renal function. Guideline-directed long-term therapy?

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