Question

A 36-year-old with dyspepsia and heartburn controlled on PPI worries about long-term use. When should an attempt to step down or discontinue PPIs be considered?

Accepted Answer

After 8 weeks in patients with symptom control and without erosive esophagitis or Barrett's

Answer

Never-PPIs should be lifelong

Answer

Only after 1 year

Answer

Only if H. pylori is positive

Answer

Only if weight loss occurs

Practice question

A 36-year-old with dyspepsia and heartburn controlled on PPI worries about long-term use. When should an attempt to step down or discontinue PPIs be considered?