Question

A 29-year-old with erythema migrans after a documented Ixodes tick bite in New England presents within 48 hours of tick removal. Which approach is recommended?

Accepted Answer

Single 200-mg dose doxycycline as post-exposure prophylaxis because attachment exceeded 36 hours

Answer

Amoxicillin 500 mg TID for 14 days as PEP

Answer

No prophylaxis; observe only regardless of risk

Answer

Two-day course of high-dose azithromycin

Answer

Topical antibiotics at bite site

Practice question

A 29-year-old with erythema migrans after a documented Ixodes tick bite in New England presents within 48 hours of tick removal. Which approach is recommended?