Question

A 52-year-old woman with newly diagnosed rheumatoid arthritis has moderate-to-high disease activity and no contraindications to therapy. She is DMARD-naive. What is the recommended initial treatment?

Accepted Answer

Methotrexate monotherapy with folic acid

Answer

Hydroxychloroquine monotherapy

Answer

Sulfasalazine monotherapy

Answer

Glucocorticoids alone for 3 months

Answer

TNF inhibitor monotherapy as first-line

Practice question

A 52-year-old woman with newly diagnosed rheumatoid arthritis has moderate-to-high disease activity and no contraindications to therapy. She is DMARD-naive. What is the recommended initial treatment?