A 58-year-old man reports three gout flares in the past year. Serum urate is 9.2 mg/dL between flares, eGFR 70 mL/min/1.73 m2. What is the best disease-modifying approach?AStart febuxostat 80 mg daily as first-lineBBegin probenecid 500 mg twice dailyCInitiate allopurinol 100 mg daily and titrate to serum urate <6 mg/dL with anti-inflammatory prophylaxisDTreat flares only; avoid urate-lowering therapy unless tophi developEStart pegloticase nowCheck my answer