Question

A 68-year-old man has an initial episode of non-fulminant Clostridioides difficile infection (WBC 12,000/µL; creatinine baseline). Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO BID for 10 days

Answer

Metronidazole 500 mg PO TID for 10 days

Answer

Bezlotoxumab monotherapy

Answer

Probiotics alone

Answer

Oral vancomycin taper-pulse regimen as first-line

Practice question

A 68-year-old man has an initial episode of non-fulminant Clostridioides difficile infection (WBC 12,000/µL; creatinine baseline). Best initial therapy?