Question

A 72-year-old man with nonvalvular atrial fibrillation, hypertension, and diabetes (CHA₂DS₂-VASc = 3) has creatinine clearance 60 mL/min. Which anticoagulation is most appropriate?

Accepted Answer

Apixaban 5 mg twice daily

Answer

Warfarin titrated to INR 2.5-3.5

Answer

Aspirin 81 mg daily

Answer

Dual antiplatelet therapy with aspirin and clopidogrel

Answer

No antithrombotic therapy is needed

Practice question

A 72-year-old man with nonvalvular atrial fibrillation, hypertension, and diabetes (CHA₂DS₂-VASc = 3) has creatinine clearance 60 mL/min. Which anticoagulation is most appropriate?