Question

A 75-year-old with AF (CHA₂DS₂-VASc 5) on apixaban needs elective cholecystectomy (moderate bleeding risk). Renal function is normal. Per perioperative antithrombotic guidance, how should apixaban be managed?

Accepted Answer

Hold apixaban 48 hours before surgery; no bridging

Answer

Continue apixaban without interruption

Answer

Hold apixaban 24 hours before surgery; no bridging

Answer

Hold apixaban and bridge with therapeutic LMWH

Answer

Switch to warfarin 1 week prior

Practice question

A 75-year-old with AF (CHA₂DS₂-VASc 5) on apixaban needs elective cholecystectomy (moderate bleeding risk). Renal function is normal. Per perioperative antithrombotic guidance, how should apixaban be managed?