Question

A 58-year-old with recurrent gouty arthritis has sUA 8.4 mg/dL between flares. No CKD. Which urate-lowering strategy is recommended?

Accepted Answer

Start allopurinol 300 mg/day immediately

Answer

Start allopurinol ≤100 mg/day and titrate to serum urate <6 mg/dL with anti-flare prophylaxis

Answer

Start febuxostat 80 mg/day without prophylaxis

Answer

Urate-lowering therapy only during flares

Answer

Probenecid first-line for all patients

Practice question

A 58-year-old with recurrent gouty arthritis has sUA 8.4 mg/dL between flares. No CKD. Which urate-lowering strategy is recommended?