Question

A 57-year-old inpatient with initial non-severe Clostridioides difficile infection (≥3 unformed stools/day, positive toxin) and no contraindications is being treated. What is the best first-line antibiotic?

Accepted Answer

Rifaximin 550 mg TID for 10 days

Answer

Metronidazole 500 mg TID for 10 days

Answer

Vancomycin 125 mg QID for 10 days

Answer

Fidaxomicin 200 mg BID for 10 days

Answer

Probiotics alone

Practice question

A 57-year-old inpatient with initial non-severe Clostridioides difficile infection (≥3 unformed stools/day, positive toxin) and no contraindications is being treated. What is the best first-line antibiotic?