Question

A 48-year-old woman with her first episode of non-severe Clostridioides difficile infection (WBC 11,000/µL, creatinine normal) seeks treatment. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO BID × 10 days

Answer

Metronidazole 500 mg PO TID × 10 days

Answer

Vancomycin 125 mg PO QID × 10 days only if fidaxomicin unavailable

Answer

Fecal microbiota transplantation now

Answer

Stop antibiotics and observe only

Practice question

A 48-year-old woman with her first episode of non-severe Clostridioides difficile infection (WBC 11,000/µL, creatinine normal) seeks treatment. Best initial therapy?