Question

A 63-year-old with T2D and CKD eGFR 32 mL/min/1.73 m² is taking metformin 1,000 mg BID. What is appropriate regarding metformin?

Accepted Answer

Continue while eGFR ≥30; discontinue if eGFR falls <30

Answer

Continue at same dose indefinitely

Answer

Increase dose to maintain A1c goal

Answer

Stop at eGFR <45

Answer

Use metformin regardless of eGFR because lactic acidosis is rare

Practice question

A 63-year-old with T2D and CKD eGFR 32 mL/min/1.73 m² is taking metformin 1,000 mg BID. What is appropriate regarding metformin?