Question

A 52-year-old with recurrent gout flares (3 in the past year) has serum urate 8.9 mg/dL, eGFR 70 mL/min/1.73 m². What long‑term approach is recommended?

Accepted Answer

Allopurinol 100 mg daily with treat‑to‑target <6 mg/dL and flare prophylaxis

Answer

Probenecid as first-line ULT

Answer

Febuxostat only if serum urate >10 mg/dL

Answer

Avoid starting ULT until he is flare‑free for 1 year

Answer

Colchicine 0.6 mg daily as sole long‑term therapy

Practice question

A 52-year-old with recurrent gout flares (3 in the past year) has serum urate 8.9 mg/dL, eGFR 70 mL/min/1.73 m². What long‑term approach is recommended?