Question

A 34-year-old woman presents with abdominal pain and watery stools after clindamycin therapy. She is hypotensive with WBC 28,000/µL and creatinine 2.2 mg/dL. CT shows toxic megacolon absent. Which C. difficile therapy is preferred?

Accepted Answer

Oral vancomycin 125 mg QID (fidaxomicin not preferred for fulminant disease)

Answer

000/µL and creatinine 2.2 mg/dL. CT shows toxic megacolon absent. Which C. difficile therapy is preferred?

Answer

Fidaxomicin 200 mg BID for 10 days

Answer

Metronidazole monotherapy

Answer

Probiotics and observation

Practice question

A 34-year-old woman presents with abdominal pain and watery stools after clindamycin therapy. She is hypotensive with WBC 28,000/µL and creatinine 2.2 mg/dL. CT shows toxic megacolon absent. Which C. difficile therapy is preferred?