Question

A 55-year-old with dyspepsia completed quadruple therapy for H. pylori. He asks about PPI discontinuation before test of cure. What is advised?

Accepted Answer

Hold PPI for ~2 weeks before urea breath or stool antigen test

Answer

Continue PPI; it does not affect testing

Answer

Hold PPI for 24 hours only

Answer

Switch to H2 blocker indefinitely

Answer

Use serology to confirm cure regardless of PPI use

Practice question

A 55-year-old with dyspepsia completed quadruple therapy for H. pylori. He asks about PPI discontinuation before test of cure. What is advised?