Question

A 72-year-old with nonvalvular AF on apixaban (CrCl 80 mL/min) is scheduled for elective colectomy (high bleeding risk). What is the best perioperative plan?

Accepted Answer

Stop apixaban 48 hours before and restart about 48 hours after if hemostasis is secure

Answer

Continue apixaban through surgery

Answer

Hold apixaban only on the morning of surgery

Answer

Bridge with therapeutic LMWH after stopping apixaban

Answer

Stop apixaban 4 days before and resume 7 days after

Practice question

A 72-year-old with nonvalvular AF on apixaban (CrCl 80 mL/min) is scheduled for elective colectomy (high bleeding risk). What is the best perioperative plan?