Question

A 66-year-old with COPD (frequent exacerbations) has blood eosinophils 360/µL despite LABA/LAMA therapy. What is the preferred pharmacologic escalation?

Accepted Answer

Add inhaled corticosteroid to create LABA/LAMA/ICS triple therapy

Answer

Switch to ICS monotherapy

Answer

Continue LABA/LAMA without change

Answer

Start roflumilast and stop bronchodilators

Answer

Replace LAMA with short-acting muscarinic antagonist only

Practice question

A 66-year-old with COPD (frequent exacerbations) has blood eosinophils 360/µL despite LABA/LAMA therapy. What is the preferred pharmacologic escalation?