Question

A 72-year-old has a first recurrence of nonsevere C. difficile infection. Best therapy now?

Accepted Answer

Fidaxomicin 200 mg PO BID × 10 days (preferred)

Answer

Metronidazole 500 mg PO TID × 10 days

Answer

Vancomycin 125 mg PO QID × 10 days with taper/pulse

Answer

Rifaximin 200 mg TID × 10 days as monotherapy

Answer

Bezlotoxumab alone

Practice question

A 72-year-old has a first recurrence of nonsevere C. difficile infection. Best therapy now?